Debbie C Thurmond Selected Research

Insulin Resistance

12/2023	A Novel Role for DOC2B in Ameliorating Palmitate-Induced Glucose Uptake Dysfunction in Skeletal Muscle Cells via a Mechanism Involving β-AR Agonism and Cofilin.
4/2022	Mechanisms by Which Skeletal Muscle Myokines Ameliorate Insulin Resistance.
1/2022	Changes in Skeletal Muscle PAK1 Levels Regulate Tissue Crosstalk to Impact Whole Body Glucose Homeostasis.
1/2022	Enrichment of the exocytosis protein STX4 in skeletal muscle remediates peripheral insulin resistance and alters mitochondrial dynamics via Drp1.
1/2022	Exocytosis Proteins: Typical and Atypical Mechanisms of Action in Skeletal Muscle.
1/2020	Role of Skeletal Muscle in Insulin Resistance and Glucose Uptake.
1/2019	DOC2B promotes insulin sensitivity in mice via a novel KLC1-dependent mechanism in skeletal muscle.
11/2017	The actin-related p41ARC subunit contributes to p21-activated kinase-1 (PAK1)-mediated glucose uptake into skeletal muscle cells.
1/2017	Promoting Glucose Transporter-4 Vesicle Trafficking along Cytoskeletal Tracks: PAK-Ing Them Out.
1/2017	Exocytosis proteins as novel targets for diabetes prevention and/or remediation?

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Debbie C Thurmond Research Topics

Disease

20	Insulin Resistance 12/2023 - 01/2003
17	Type 2 Diabetes Mellitus (MODY) 04/2022 - 03/2010
7	Hyperglycemia 01/2024 - 05/2011
5	Glucose Intolerance 01/2022 - 08/2003
4	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 12/2021 - 01/2017
4	Obesity 01/2020 - 03/2010
3	Inflammation (Inflammations) 04/2022 - 05/2011
2	Metabolic Diseases (Metabolic Disease) 04/2022 - 01/2020
2	Neoplasms (Cancer) 01/2017 - 12/2011
1	Pancreatitis 01/2018
1	Prediabetic State (Prediabetes) 01/2018
1	Alzheimer Disease (Alzheimer's Disease) 01/2017
1	Necrosis 01/2017
1	B-Cell Lymphoma (Lymphoma, B Cell) 10/2016
1	Hypertension (High Blood Pressure) 02/2015
1	Carcinogenesis 12/2011

Drug/Important Bio-Agent (IBA)

19	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 08/2003
14	Insulin (Novolin)FDA Link 01/2022 - 08/2003
10	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2003
4	Qa-SNARE Proteins (Syntaxin)IBA 01/2022 - 03/2010
2	Phosphotransferases (Kinase)IBA 01/2021 - 10/2016
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 01/2017
2	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 11/2017 - 11/2014
1	LipidsIBA 01/2024
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2024
1	PalmitatesIBA 12/2023
1	Androgen Receptors (Androgen Receptor)IBA 01/2023
1	MyokinesIBA 04/2022
1	SNARE Proteins (SNAREs)IBA 01/2022
1	cdc42 GTP-Binding ProteinIBA 01/2021
1	GTP Phosphohydrolases (GTPases)IBA 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2019
1	erythromycin propionate-N-acetylcysteinateIBA 10/2018
1	Sincalide FDA Link 01/2018
1	CeruletideIBA 01/2018
1	CytokinesIBA 01/2017
1	Indicators and Reagents (Reagents)IBA 01/2017
1	InterferonsIBA 01/2017
1	Streptozocin (Streptozotocin)FDA Link 02/2015
1	Actins (F Actin)IBA 11/2014
1	Actin Depolymerizing Factors (Cofilins)IBA 12/2011
1	p21-Activated KinasesIBA 12/2011
1	Protein Isoforms (Isoforms)IBA 03/2010
1	Soluble N-Ethylmaleimide-Sensitive Factor Attachment ProteinsIBA 11/2007
1	Munc18 ProteinsIBA 03/2005
1	CarbohydratesIBA 03/2005
1	Tetracycline (Achromycin)FDA LinkGeneric 08/2003
1	Glucosamine (Dona)IBA 01/2003

Therapy/Procedure

2	Therapeutics 01/2020 - 05/2014
1	Transplantation 05/2014